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EAE-PLP
Model: PLP139-151 induced relapsing-remitting EAE in SJL/J mice
Animal: SJL/J
Immunogen: PLP139-151 peptide
Study duration: 40-50 days (in life)
Pathological features:
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Relapse_remitting model
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Inflammatory Infiltration and de-myelination in CNS
Suitability:
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De-myelination,neuron regeneration and T cell response
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Not suited for study of B cell involvement/intervention
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Efficacy study against relapse
Parameter measures:
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Body weight
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clinical score
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Histo-pathological assessment
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Cytokine ELISA (optional)
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RT-qPCR (optional)
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IHC (optional)
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P.R.China
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